Experimental characterisation of the solid stress in tumours.
Left: Expected solid stress accumulated in a solid tumour. Cells are compressed in the center isotropically, while cells at the periphery are stretched tangentially and compacted radially. Middle: Cuting the tumour along the long axis will release the stress. Right: Stress release induces the bulging of the central part (black arrows, compressed zone) and constriction of the periphery (green arrows, stretched area). Adapted from [96]