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. 2020 Jun;63:69–80. doi: 10.1016/j.semcancer.2019.05.004

Fig. 3.

Fig. 3

Experimental characterisation of the solid stress in tumours.

Left: Expected solid stress accumulated in a solid tumour. Cells are compressed in the center isotropically, while cells at the periphery are stretched tangentially and compacted radially. Middle: Cuting the tumour along the long axis will release the stress. Right: Stress release induces the bulging of the central part (black arrows, compressed zone) and constriction of the periphery (green arrows, stretched area). Adapted from [96]