Table 2.
Information on tuberculosis and COVID-19 in 8 patients who died.
| #Case | Time between TB and COVID-19 diagnosis (no. of days) | COVID-19 symptoms/MuLBSTA score at diagnosis | COVID-19 therapy (antivirals, steroids, maximum oxygen flow received, ventilation, etc.) | Imaging during TB/COVID-19 course | Time between COVID-19 diagnosis and death; cause of death; hospital admission (no. of days) | Comments |
|---|---|---|---|---|---|---|
| 1 | 121 | None, MuLBSTA score 8 | Hydroxychloroquine, parnaparine 4250 IU, oxygen through Venturi Mask 60% 12 l/min | Not done | 10 days, respiratory failure 130 days at hospital | BCG vaccinated COVID-19 diagnosis after contact tracing due to a case in same ward. Patient developed fever and dyspnoea later. |
| 2 | 19 | None, MuLBSTA score 15 | Hydroxychloroquine, lopinavir/ritonavir, enoxaparine 4000 IU, dexamethasone 8 mg × 2, oxygen through non-rebreather, 15 l/min | C-X ray: new bilateral pulmonary infiltrates | 13 days, respiratory failure 31 days at hospital | BCG vaccinated COVID-19 diagnosis after contact tracing due to a case in same ward. Patient developed fever and dyspnoea later. |
| 3 | 1205 | Fever, MuLBSTA score: 5 | Hydroxychloroquine, azithromycin, oxygen through face mask | CT/C-X ray: unilateral infiltrate | 8 days, cachexia and respiratory failure 8 days at hospital | BCG status unknown COVID-19 major determinant of death, complicating the poor clinical conditions due to multiple and severe co-morbidities |
| 4 | 7 | Cough, dyspnoea, tiredness, MuLBSTA score:12 | Hydroxychloroquine, oxygen through non-rebreather mask, 15 l/min | CT: unilateral crazy paving developing on pre-existing lesions | 6 days respiratory failure 13 days at hospital | BCG vaccinated COVID-19 determinant of death |
| 5 | 12 | Fever, cough, vomit, MuLBSTA score: 11 | Hydroxychloroquine, oxygen through face mask, Hb saturation: 89% with 4 l/min | CT/C-X ray: miliary pattern | 14 days respiratory failure 24 days at hospital | BCG status unknown COVID-19 aggravated general conditions and renal fail |
| 6 | 75 | Fever, MuLBSTA score: 9 | Hydroxychloroquine, azythromycin. Hb saturation: 93%, room air | CT/C-X ray: bilateral infiltrates | 8 days, respiratory failure 82 days at hospital | BCG status unknown, COVID-19 major determinant of death; COVID-19 acquired at hospital |
| 7 | 26 | Fever (up to 39 °C), severe dyspnoea with respiratory failure, MuLBSTA score: 9 | Hydroxychloroquine. Oxygen supply from 2 to 10 l/min with reservoir. | C-X ray (at bed): bilateral excavated lung thickening, tree in bud (right lung) | 6 days Respiratory failure 32 days at hospital |
Not BCG vaccinated. COVID-19 accelerated death, although the patients was already very compromised since admission, COVID-19 acquired at hospital |
| 8 | 4 days (COVID-19 diagnosed before TB) | Fever, cough, MuLBSTA score: 15 | Hydroxychloroquine, lopinavir/ritonavir, azythromicin, piperacilin-tazobactam, Hb saturation: 99% with re-breather mask, 15 l/min, non-invasive ventilation performed | CT/C-X ray: bilateral infiltrates | 12 days Respiratory failure 12 days |
BCG: unknown COVID-19 accelerated death, although the patients was already very compromised since admission COVID-19 acquired at hospital |
BCG: Bacillus Calmette-Guérin; COVID-19: COronaVIrus Disease 19; CT: computed tomography; C-X ray: chest radiography; Hb: hemoglobine; IU: international unit; MuLBSTA: multilobular infiltration, hypo-lymphocytosis, bacterial coinfection, smoking history, hyper-tension and age; TB: tuberculosis.