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. 2020 May 7;12:3203–3210. doi: 10.2147/CMAR.S249775

Table 1.

Baseline Characteristics of SCCHN Patients (N=323)

Clinicopathological Variables All (N = 323) Healthy BMI (N = 137) Overweight (N = 109) Obese (N = 77) P
Age (y)
 ≥60 y 205 (63.47%) 81 (59.12%) 71 (65.14%) 53 (68.83%)
 <60 y 118 (36.53%) 56 (40.88%) 38 (34.86%) 24 (31.17%) 0.333
Gender
 Female 117 (36.22%) 50 (36.50%) 39 (35.78%) 28 (36.37%)
 Male 206 (63.78%) 87 (63.50%) 70 (64.22%) 49 (63.63%) 0.993
Alcohol
 Frequent 189 (58.51%) 83 (60.58%) 65 (59.63%) 41 (53.25%)
 Occasional 92 (28.48%) 40 (29.20%) 32 (29.36%) 20 (25.97%)
 Never 42 (13.01%) 14 (10.22%) 12 (11.01%) 16 (20.78%) 0.245
Smoking
 Frequent 177 (54.80%) 80 (58.39%) 58 (53.21%) 39 (50.65%)
 Occasional 89 (27.55%) 38 (27.74%) 29 (26.61%) 22 (28.58%)
 Never 57 (17.65%) 19 (0.138%) 22 (20.18%) 16 (20.78%) 0.624
HPV-16 Ssub-Type
 Positive 8 (2.48%) 4 (2.92%) 2 (1.83%) 2 (2.58%)
 Negative 315 (97.52%) 133 (97.08%) 107 (98.17%) 75 (97.42%) 0.860
Pre-Diagnosis Weight Loss
 Yes 206 (63.78%) 87 (63.50%) 75 (68.81%) 44 (57.14%)
 No 117 (36.22%) 50 (36.50%) 34 (31.19%) 33 (42.86%) 0.264
Diabetes Mellitus
 Yes 32 (9.91%) 5 (3.65%) 13 (7.41%) 14 (20.51%)
 No 291 (90.09%) 132 (96.35%) 96 (92.59%) 63 (79.49%) 0.002
Coronary Heart Disease
 Yes 35 (10.84%) 6 (4.38%) 12 (11.01%) 17 (15.60%)
 No 288 (89.16%) 131 (95.62%) 97 (88.99%) 60 (84.40%) 0.000
T Stage
 T1/T2 204 (63.16%) 93 (67.88%) 60 (55.05%) 51 (66.23%)
 T3/T4 119 (36.84%) 44 (32.12%) 49 (44.95%) 26 (33.77%) 0.095
N Stage
 N0 202 (62.54%) 85 (62.04%) 68 (62.39%) 49 (63.64%)
 N1–3 81 (25.08%) 36 (26.28%) 28 (25.69%) 17 (22.08%)
 N x 40 (12.38%) 16 (11.68%) 13 (11.93%) 11 (14.29%) 0.953
Clinical Stage
I/II 231 (71.52%) 98 (71.53%) 77 (70.64%) 56 (72.73%)
III/IV 92 (28.48%) 39 (28.47%) 32 (29.36%) 21 (27.27%) 0.893

Abbreviations: BMI, body mass index; HPV, human papilloma virus; T, tumor; N, node; SCCHN, squamous cell carcinoma of head and neck.