Table 4.
Cox Univariatable and Multivariatable Analysis for SCCHN 3-y Overall Survival (N=323)
| Variables | HR | Cox-Univariatable | P | HR | Cox-Multivariatable | P |
|---|---|---|---|---|---|---|
| 95% CI | 95% CI | |||||
| Age (y) | ||||||
| <60 y | 1.000 | Ref. | – | – | – | – |
| ≥60 y | 1.098 | 0.523–2.709 | 0.801 | – | – | – |
| Gender | ||||||
| Female | 1.000 | Ref. | – | – | – | – |
| Male | 1.872 | 0.898–2.751 | 0.199 | – | – | – |
| BMI | ||||||
| Healthy | 1.000 | Ref. | - | 1.000 | Ref. | - |
| Overweight | 1.336 | 0.572–2.892 | 0.681 | 2.906 | 1.092–6.448 | 0.808 |
| Obese | 1.129 | 0.408–2.404 | 0.520 | 1.791 | 0.553–5.471 | |
| Alcohol | ||||||
| Never | 1.000 | Ref. | – | – | – | – |
| Occasional | 1.238 | 0.488–2.612 | 0.690 | – | – | – |
| Frequent | 0.909 | 0.400–1.774 | 0.594 | – | – | – |
| Smoking | ||||||
| Never | 1.000 | Ref. | – | – | – | – |
| Occasional | 1.218 | 0.602–2.791 | 0.677 | – | – | – |
| Frequent | 0.883 | 0.451–2.318 | 0.709 | – | – | – |
| T Stage | ||||||
| T1/T2 | 1.000 | Ref. | – | 1.000 | Ref. | – |
| T3/T4 | 3.563 | 2.071–9.053 | 0.023 | 4.981 | 1.453–13.609 | 0.019 |
| N Stage | ||||||
| N0 | 1.000 | Ref. | – | 1.000 | Ref. | – |
| N1–3 | 4.561 | 2.417–11.829 | 0.005 | 8.152 | 1.352–12.780 | 0.001 |
| Clinical Stage | ||||||
| I/II | 1.000 | Ref. | – | 1.000 | Ref. | – |
| III/IV | 6.554 | 3.809–13.296 | 0.002 | 3.772 | 1.393–8.668 | 0.001 |
Abbreviations: HR, hazard ratio; CI, confidence interval; BMI, body mass index; T, tumor; N, node; SCCHN, squamous cell carcinoma of head and neck.