FIGURE 3.

Predicting growth rates from RNA‐seq data. A, We used data from the NCI60 cell line panel to develop a linear regression equation to predict tumor growth rates from RNA‐seq data. B, We next used data from the SCANB breast cancer transcriptomic study to relate PCNA metagene expression to mitotic index (or Ki76 staining). These regression equations allowed us to predict (C) mitotic index and (D) specific growth rates from TCGA BRCA dataset and (E) mitotic index and (F) specific growth rates from the SCANB breast cancer dataset