Fig 3.

Kaplan-Meier curves of time to alleviation of clinical symptoms with standard of care (SOC) plus hydroxychloroquine (HCQ) versus SOC alone in intention to treat population. Data shown are for 55 patients with symptoms assigned to SOC plus HCQ and 64 assigned to SOC. Probability of alleviation of symptoms by 28 days was similar (P=0.97) in patients with SOC with (59.9%, 95% confidence interval 45.0% to 75.3%) and without HCQ (66.6%, 39.5% to 90.9%). Difference between groups was –6.6% (95% CI –41.3% to 28.0%). Median time to alleviation of clinical symptoms was similar in SOC plus HCQ group and SOC group (19 v 21 days; hazard ratio 1.01, 95% confidence interval 0.59 to 1.74; P=0.97 by log rank test). Data from patients who did not have alleviation of symptoms were censored (tick marks) at last visit date