Table 3.

Binding affinity of (±)-citalopram for the [³H]imipramine sites at the respective hα3β4 and hα4β2 AChRs in the desensitized state.

AChR subtype	Ki, μM a	nHb
hα3β4	1.8 ± 0.1	0.74 ± 0.04
hα4β2	4.1 ± 0.3	0.72 ± 0.03

^aThe IC₅₀ values obtained from Figure 4 were transformed into K_i values using Eq. (2).

^bHill coefficient.