Table 2.
After stratification for the dVNTR genotypes, the association of uVNTR polymorphism with several quantitative measures became significant.
| Phenotype | Strata | Genotypes | n | Mean | Dif | 95% CI | P-value | AIC |
|---|---|---|---|---|---|---|---|---|
| Years of smoking | 10/10 | 3/3 | 61 | 31.9 | 0 | NA | ||
| 4/4 | 542 | 25.0 | −6.9 | –11.6 – −2.1 | 0.005 | 5207 | ||
| 9/9 | 3/3 | 673 | 25.1 | 0 | ||||
| 4/4 | 67 | 31.8 | 6.69 | 1.9 – 11.4 | 0.006 | 6463 | ||
| Fagerström Nicotine Dependence (FTND) score | 10/10 | 3/3 | 60 | 4.8 | 0 | NA | ||
| 4/4 | 540 | 3.9 | −0.9 | −1.6 – −0.3 | 0.003 | 2741 | ||
| 9/9 | 3/3 | 670 | 4.06 | 0 | ||||
| 4/4 | 67 | 4.08 | 0.02 | −0.6 – 0.6 | 0.9 | 3393 | ||
| The age of smoking initiation | 10/10 | 3/3 | 61 | 20.3 | 0 | NA | ||
| 4/4 | 542 | 18.6 | −1.7 | −2.7 – −0.6 | 0.003 | 3413 | ||
| 9/9 | 3/3 | 672 | 18.7 | 0 | ||||
| 4/4 | 67 | 18.1 | −0.6 | −1.8 – 0.6 | 0.3 | 4433 | ||
| F1 score, time to the first cigarette after wake up | 10/10 | 3/3 | 60 | 1.9 | 0 | NA | ||
| 4/4 | 537 | 1.5 | −0.4 | −0.7 – −0.1 | 0.006 | 1824 | ||
| 9/9 | 3/3 | 667 | 1.5 | 0 | ||||
| 4/4 | 67 | 1.6 | 0.13 | −0.1 – 0.4 | 0.3 | 2218 | ||
| Number of quit attempts | 10/10 | 3/3 | 60 | 0.6 | 0 | NA | ||
| 4/4 | 533 | 1.0 | 0.4 | 0.1–0.6 | 0.01 | 1729 | ||
| 9/9 | 3/3 | 666 | 1.0 | 0 | ||||
| 4/4 | 66 | 1.1 | 0.1 | −0.2 – 0.4 | 0.5 | 2301 |