Table 3.

The diagnostic performance of 15 non-invasive fibrosis indices in the detection of cirrhosis in hepatitis-B-related HCC.

Variable	Cut-off value	AUC	95% CI	Sensitivity (%)	Specificity (%)	P
AAR	0.6362	0.509	0.459 to 0.559	18.6	87.8	0.7908
AARP	0	0.592	0.543 to 0.640	69.7	48.8	0.0026
AARPRI	0.9245	0.622	0.572 to 0.669	50.2	72.0	0.0002
API	5	0.651	0.602 to 0.697	60.4	68.3	<0.0001
APRI	0.4511	0.707	0.660 to 0.751	56.7	76.8	<0.0001
CDS	5	0.661	0.613 to 0.707	58.8	63.4	<0.0001
FIB-4 Index	1.5597	0.686	0.638 to 0.731	66.6	64.6	<0.0001
Fibro-α Score	1.3548	0.528	0.478 to 0.578	83.2	29.3	0.4682
Fibrosis Index	2.25	0.692	0.645 to 0.737	57.0	75.6	<0.0001
Fibro Q	3.1624	0.642	0.593 to 0.689	58.2	64.6	<0.0001
GUCI	0.5105	0.722	0.676 to 0.765	55.7	80.5	<0.0001
King Score	8.254	0.711	0.664 to 0.755	77.7	54.9	<0.0001
P2/MS	78.6612	0.683	0.635 to 0.728	67.8	62.2	<0.0001
PLASA Score	0.2671	0.616	0.567 to 0.664	87.3	35.4	0.0019
Pohl Score	0	0.566	0.516 to 0.615	24.1	89.0	0.0018

AAR: aspartate aminotransferase to alanine aminotransferase ratio; AST: aspartate aminotransferase; PLT: platelet count; AARP: AAR-platelet score; AARPRI: AAR-to-platelet ratio index; API: age-platelet index; APRI: AST to platelet ratio index; CDS: cirrhosis discriminant score; FIB-4 Index: fibrosis index based on the four factors; Fibro Q: fibro-quotient; GUCI: Goteburg University Cirrhosis Index; PLASA: platelet-AST-age; AUC: area under the receiver operating characteristic curve; CI: confidence interval.