Table 2.

Indicators of systemic hemodynamics following administration of a CNP suspension.

	Saline		CNP 2 mg/kg
	MAP, mm Hg	HR, bpm	MAP, mm Hg	HR, bpm
Baseline	136 [134–148]	396 [372–420]	121 [105–142]	396 [366–408]
Beginning of administration	136 [130–151]	396 [365–420]	134 [110–146]	384 [361–402]
End of administration	139 [126–147]	396 [366–420]	138 [115–145]	395 [364–402]
5 min after administration	126 [117–148]	384 [344–420]	143 [120–144] *p = 0.026	396 [371–401]
30 min after administration	134 [110–146]	384 [361–402]	136 [118–141]	396 [383–413]
60 min after administration	–	–	124 [104–137]	408 [354–417]

*—p compared to baseline (paired Wilcoxon test). Median and the 25th and 75th percentiles (Me [25–75%]).