Figure 5.

(a) The microcomputed tomography (μCT) image of ectopic bone formed at three weeks after subcutaneous implantation of scaffold with recombinant human bone morphogenetic protein-2 (rhBMP-2) in a mouse model. Ectopic bone formation comparable to that of the MWCNT block was found in the polyethylene terephthalate (PET)-reinforced collagen scaffold. Image is modified from a study by Tanaka et al. [74]. (b) In a mouse calvarial defect model, critical size bone defects were repaired with new bone in both the IP-CHA and CNTp groups. Image is modified from a study by Tanaka et al. [51].