AOP	adverse outcome pathways
BMD	benchmark dose
CDC	Centers for Disease Control and Prevention
CEBS	Chemical Effects in Biological Systems
cDNA	complementary DNA
CMAP	Connectivity Map
EAGMST	Extended Advisory Group for Molecular Screening and Toxicogenomics
ECHA	European chemicals agency
ECVAM	European Centre for the Validation of Alternative Methods
EFSA	European Food Safety Authority
eUTOPIA	A solUTion for Omics data PreprocessIng and Analysis
FAIR	Findable, Accessible, Interoperable and Reusable Data Principle
FDA	Food and Drug Administration
GEO	Gene Expression Omnibus
GO	gene ontology
GTEx	Genotype-Tissue Expression
JRC	Joint Research Centre
L1000	Library of Integrated Network-Based Cellular Signatures 1000
MIAME	Minimum Information About a Microarray Experiment
MINSEQE	Minimal Information about a high throughput SEQuencing Experiment
MOA	mechanism of action
NCT	National Center for Toxicogenomics
NCTR	National Center for Toxicological Research
NIEHS	National Institute of Environmental Health Sciences
NIH	National Institutes of Health
NIOSH	The National Institute for Occupational Safety and Health
NTP	The National Toxicology Program
OECD	Organisation for Economic Co-operation and Development
TG-GATE	Toxicogenomics Project-Genomics Assisted Toxicity Evaluation System
PCR	polymerase chain reaction
POD	point of departure
QSAR	quantitative structure activity relationship
REACH	Registration, Evaluation, Authorisation and Restriction of Chemicals
RNA-Seq	RNA sequencing
scRNA-Seq	single-cell RNA sequencing
TGx	toxicogenomics
3R	Replacement, Reduction and Refinement in animal testing