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. 2020 Apr 11;25(8):1766. doi: 10.3390/molecules25081766

Table 2.

Cancer cell lines encompassed in the NCI-60 panel with their weights calculated based on lower and upper outlier frequency in each of the predictive set’s groups, sorted by represented tissue.

Cell No. Cell Line Tumoral Tissue Type Cell line Weight Factors Cell No. Cell Line Tumoral Tissue Type Cell line Weight Factors
Upper Outliers Lower Outliers Upper Outliers Lower Outliers
1 CCRF-CEM Leukemia −4.44 0.00 31 M14 Melanoma 5.56 −2.50
2 HL-60(TB) Leukemia −20.00 5.56 32 MDA-MB-435 Melanoma 3.06 0.00
3 K-562 Leukemia 11.67 11.11 33 SK-MEL-2 Melanoma 1.81 −1.25
4 MOLT-4 Leukemia −6.94 −1.25 34 SK-MEL-28 Melanoma 11.11 −3.75
5 RPMI-8226 Leukemia −1.94 5.56 35 SK-MEL-5 Melanoma 3.06 0.00
6 SR Leukemia −6.39 5.56 36 UACC-257 Melanoma 1.81 −2.50
7 A549/ATCC NSCLC −1.25 −1.25 37 UACC-62 Melanoma 1.81 −1.25
8 EKVX NSCLC 27.78 −6.25 38 IGROV1 Ovarian 1.81 −1.25
9 HOP-62 NSCLC 0.00 4.31 39 OVCAR-3 Ovarian 0.00 3.06
10 HOP-92 NSCLC 8.61 −3.75 40 OVCAR-4 Ovarian −1.25 −7.50
11 NCI-H226 NSCLC 11.11 4.31 41 OVCAR-5 Ovarian 5.56 −2.50
12 NCI-H23 NSCLC −1.25 −1.25 42 OVCAR-8 Ovarian 0.00 −1.25
13 NCI-H322M NSCLC 27.78 −5.00 43 NCI/ADR-RES Ovarian −1.25 −14.44
14 NCI-H460 NSCLC −10.00 −1.25 44 SK-OV-3 Ovarian 9.86 9.86
15 NCI-H522 NSCLC 1.81 0.00 45 786-0 Renal −3.75 4.31
16 COLO 205 Colon 5.56 −1.25 46 A498 Renal 24.03 4.31
17 HCC-2998 Colon −2.50 −1.25 47 ACHN Renal 15.42 −5.00
18 HCT-116 Colon 4.31 4.31 48 CAKI-1 Renal 17.22 −7.50
19 HCT-15 Colon −2.50 −7.50 49 RXF 393 Renal 4.31 0.00
20 HT29 Colon 9.86 0.00 50 SN12C Renal 0.00 −1.25
21 KM12 Colon 16.67 4.31 51 TK-10 Renal 16.67 −6.25
22 SW-620 Colon 0.00 5.56 52 UO-31 Renal 3.06 −8.75
23 SF-268 CNS 0.00 0.00 53 PC-3 Prostate −1.25 −2.50
24 SF-295 CNS −1.25 0.00 54 DU-145 Prostate −2.50 −1.25
25 SF-539 CNS 4.31 5.56 55 MCF7 Breast −2.50 0.00
26 SNB-19 CNS 0.00 −0.69 56 MDA-MB-231/ATCC Breast −1.25 −5.00
27 SNB-75 CNS 6.11 −1.25 57 MDA-MB-468 Breast −3.75 0.00
28 U251 CNS −1.25 5.56 58 HS 578T Breast 7.36 −2.50
29 LOX IMVI Melanoma −3.75 0.00 59 BT-549 Breast 1.81 −3.75
30 MALME-3M Melanoma 5.56 −1.25 60 T-47D Breast −3.75 1.81

NSCLC = non-small cell lung cancer; CNS = central nervous system; NCI-60 = National Cancer Institute’s previously tested compounds on 60 tumoral cell lines.