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. 2020 Apr 9;10(4):709. doi: 10.3390/nano10040709

Table 3.

Apparent drug solubility, zeta potential, and pH of nepafenac eye drop suspensions.

Formulation Apparent Drug Solubility
at 25 °C (mg/mL)
Dissolved Drug Content (%) Zeta Potential (mV) pH
A1 1.87 ± 0.03 62.33 −10.9 ± 0.6 6.08 ± 0.23
A2 1.95 ± 0.02 65.00 −10.4 ± 0.3 6.18 ± 0.05
A3 2.23 ± 0.01 74.33 −6.4 ± 0.8 6.09 ± 0.03
A4 1.91 ± 0.02 63.66 −12.1 ± 1.4 6.21 ± 0.09
A5 2.50 ± 0.02 83.33 −7.8 ± 0.9 6.07 ± 0.02
A6 1.89 ± 0.05 63.00 −27.4 ± 1.7 6.13 ± 0.33
A7 1.68 ± 0.01 56.00 −14.4 ± 1.4 6.01 ± 0.23
A8 1.95 ± 0.02 65.00 −14.7 ± 1.2 6.16 ± 0.15
A9 2.61 ± 0.02 87.00 −6.9 ± 1.4 6.08 ± 0.05