Table 3.
0% | 25% | 50% | 75% | 100% | |
---|---|---|---|---|---|
TMA (μM) | 0.70 | 1.37 | 2.07 | 2.62 | 4.39 |
TMAO (μM) | 52.0 | 243.7 | 379.0 | 648.1 | 1141.0 |
TMAO/TMA (mol/mol) | 66 | 132 | 208 | 315 | 506 |
TMA/creatinine (mmol/mol) | 0.05 | 0.09 | 0.13 | 0.23 | 1.43 |
TMAO/creatinine (mmol/mol) | 11.3 | 22.5 | 33.8 | 45.6 | 106.4 |
Twenty-nine healthy human subjects’ urine samples were collected to measure TMA and TMAO. Urine creatinine was measured by LC/MS following the protocol as reported previously [10].