FIGURE 2.

SVR-based prediction of EYO in autosomal-dominant Alzheimer’s disease and feature selection probabilities. (A) Scatterplot showing the association between observed EYO scores and AFGC-predicted estimated years to symptom onset (EYO) scores in DIAN-MC. (B) Selection probabilities of the AFGC model indicate the percentage of final CV1 models (see step in Figure 1B) that included the respective region of interest/biomarker. Features were selected in the DIAN-MC cohort during each CV1 cycle based on the correlation with the outcome measure (ie, EYO)