Table 2.
Clinical features of patients suspected with BCNU-induced pneumonitis
| Patient sex/age | Disease subtype | Days from HDC/auto-SCT | # of events | Symptoms | Radiologic findings | Prior chest RT | Prior bleomycin | Prior rituximab | Corticosteroid therapy | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|
| F/13.1 | BL | 37 | 1 | Fever, cough | Bilateral multifocal patchy GGO, pleural effusion | (−) | (−) | (−) | (−) | Recovered |
| F/17.3 | DLBL | 55 | 1 | Fever, blood-tinged sputum | Multifocal patchy GGO, pleural effusion | (−) | (−) | (−) | (−) | Recovered |
| M/6.2 | HD | 26 | 1 | Fever | Bilateral interlobular septal thickening, pleural effusion | (−) | (+) | (−) | (−) | ILD |
| M/3.6 | ALCL | 26 | 1 | Fever, tachypnea | Bilateral multifocal nodular consolidations and GGO | (−) | (−) | (−) | (−) | Dead |
| M/14.1 | HD | 44 | 1 | Fever, cough, dyspnea | Bilateral patchy GGO, pleural effusion | (−) | (+) | (−) | (−) | Recovered |
| M/17.1 | DLBL | 48 | 1 | Fever, chest pain, dyspnea | Bilateral patchy GGO, pleural effusion | (−) | (−) | (−) | (−) | Recovered |
| M/4.0 | BL | 30 | 1 | Fever, cough, sputum | Bilateral patchy GGO | (−) | (−) | (−) | (−) | Recovered |
| M/13.3 | HD | 34 | 2 | Dyspnea | Bilateral multifocal patchy GGO, pleural effusion | (−) | (+) | (−) | (+) | Recovered |
| M/13.5 | DLBL | 38 | 1 | Sputum | Bilateral multifocal GGO | (−) | (−) | (+) | (+) | Recovered |
ALCL anaplastic large cell lymphoma, BAL bronchoalveolar lavage, BL Burkitt lymphoma, DLBL diffuse large B-cell lymphoma, GGO ground glass opacity, HD Hodgkin’s disease, ILD interstitial lung disease