. 2019 May 10;32(1):226–237. doi: 10.1007/s12028-019-00730-7

Table 2.

Hyperosmolar therapies for ICP management

	Equiosmolar dose	Osmolarity	Sodium concentration	Usual dose
2% sodium chloride	3.5 mL/kg	684 mOsm/L	342 mEq/L	250–500 mL
2% sodium chloride/sodium acetate	4.1 mL/kg	588 mOsm/L	294 mEq/L	250–500 mL
3% sodium chloride	2.5 mL/kg	1027 mOsm/L	513 mEq/L	250–500 mL
7.5% sodium chloride/sodium acetate	1 mL/kg	2196 mOsm/L	1283 mEq/L	50–250 mL
8.4% sodium bicarbonate	1 mL/kg	2002 mOsm/L	1000 mEq/L	50–100 mL
23.4% sodium chloride	0.3 mL/kg	8008 mOsm/L	4004 mEq/L	30 mL
Mannitol 20%	0.5–1 g/kg	1098 mOsm/L	n/a	0.5–1 mg/kg