Fig. 5.

The PR79L9 virus is sensitive to 8D6 iGL. a Blocking of AP33, AR3C, and 8D6 by human plasma. Data are presented as the percentage inhibition. Samples included acute plasma samples from 10 patients who were able to spontaneously clear HCV infection, plasma samples from 32 patients with chronic 1b infection, samples from 13 patients with chronic 2a infection, and nine samples from healthy subjects participating as controls. b HCVcc neutralizing activity scanning of 8D6 iGL. c Binding of 8D6 iGL to various purified E2 proteins by ELISA. All data are representative of two independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, NS, not significant (two-tailed Student’s t test)