Table 3.
Maternal plasma antioxidants and biomarkers of oxidative damage, according to the development of FGR or preterm labor.
| Parameter | NFG (72) | FGR (12) | p-Value | Full-Term (52) | Preterm (39) | p-Value |
|---|---|---|---|---|---|---|
| Catalase activity (U CAT/mg prot.) | 0.4 ± 0.03 | 0.5 ± 0.2 | 0.384 | 0.5 ± 0.05 | 0.4 ± 0.07 | 0.550 |
| SOD activity (U SOD/mg prot.) | 1.3 ± 0.1 | 1.1 ± 0.3 | 0.598 | 1.4 ± 0.2 | 1.2 ± 0.2 | 0.518 |
| Glutathione (mg GSH/mg prot.) | 0.7 ± 0.09 | 0.9 ± 0.2 | 0.440 | 0.8 ± 0.1 | 0.9 ± 0.1 | 0.407 |
| Thiol groups (µM GSH/mg prot.) | 4.7 ± 0.1 | 4.8 ± 0.6 | 0.684 | 4.7 ± 0.2 | 4.6 ± 0.2 | 0.778 |
| Phenolic compounds (mg GAE/L) | 300 ± 6.7 | 271 ± 26.4 | 0.149 | 290 ± 8.4 | 294 ± 10.5 | 0.805 |
| Malondialdehyde (µmol/L) | 6.5 ± 0.5 | 8.8 ± 1.7 | 0.101 | 7.2 ± 0.6 | 6.4 ± 0.6 | 0.359 |
| Carbonyl groups (nmol/mg prot.) | 0.9 ± 0.1 | 0.7 ± 0.2 | 0.530 | 0.8 ± 0.1 | 0.8 ± 0.1 | 0.626 |
Data show mean ± SEM. Sample size shown between brackets. CAT, catalase; SOD, superoxide dismutase; GSH, reduced glutathione; GAE, gallic acid equivalents; prot., protein. Student´s T test.