Table 1.
Patient characteristics. Data presented as patients who had early elevated troponin-T within the first 24 h after surgery vs patients in whom troponin-T remained <99th centile. Data are shown as absolute median (IQR) values or n (%). Odds ratio (OR) with 95% confidence intervals (CIs) shown, where applicable. COPD, chronic obstructive pulmonary disease; IQR, inter-quartile range; RCRI, Revised Cardiac Risk Index.
| Troponin, ≥15 ng L−1 | Troponin, <15 ng L−1 | OR (95% CI) | |
|---|---|---|---|
| Age (y) | 69 (59–78) | 64 (55–72) | – |
| BMI (kg m−2) | 28.0 (6.1) | 28.9 (6.5) | – |
| Female sex, n (%) | 331 (33.4) | 1621 (48.5) | 0.69 (0.63–0.76) |
| RCRI ≥2, n (%) | 238 (24.0) | 296 (8.9) | 2.71(2.32–3.17) |
| ASA ≥3, n (%) | 546 (55.0) | 821 (24.6) | 3.76 (3.24–4.36) |
| Coronary artery disease, n (%) | 234 (23.6) | 293 (8.8) | 2.69 (2.30–3.15) |
| Cardiac failure, n (%) | 29 (2.9) | 29 (0.9) | 3.37 (2.02–5.61) |
| Diabetes mellitus, insulin treated, n (%) | 70 (7.1) | 105 (3.1) | 2.25 (1.67–3.02) |
| Diabetes mellitus, tablet treated, n (%) | 149 (15.0) | 333 (10.0) | 1.51 (1.26–1.81) |
| Cirrhosis, n (%) | 8 (0.8) | 18 (0.5) | 1.50 (0.65–3.43) |
| Stroke/transient ischaemic attack, n (%) | 86 (8.7) | 169 (5.1) | 1.72 (1.34–2.20) |
| Asthma, n (%) | 83 (8.4) | 345 (10.3) | 0.81 (0.65–1.02) |
| COPD, n (%) | 111 (11.2) | 191 (5.7) | 1.96 (1.57–2.45) |
| Metastases (preop), n (%) | 40 (4.0) | 120 (3.6) | 1.12 (0.79–1.60) |
| Systolic (mm Hg) | 141 (23) | 137 (21) | – |
| Diastolic (mm Hg) | 74 (12) | 75 (13) | – |
| Heart rate (beats min−1) | 76 (14) | 76 (13) | – |
| Haemoglobin (g L−1) | 126 (19) | 134 (17) | – |
| Intraoperative | |||
| Duration of surgery (min) | 140 (80–220) | 136 (90–205) | – |
| Crystalloid (ml kg h−1) | 9.4 (6.0–14.3) | 9.3 (6.3–13.5) | – |
| Fluid including colloid (ml kg h−1) | 10.2 (6.5–15.2) | 9.9 (6.8–14.3) | – |
| Estimated blood loss >500 ml, n (%) | 114 (11.5) | 279 (8.3) | – |
| Blood administered, n (%) | 83 (8.3) | 123 (3.7) | – |
| Postoperative | |||
| Planned critical care, n (%) | 314 (31.7) | 678 (20.3) | 1.56 (1.39–1.75) |