Table 2.
Postoperative morbidity 72 h after surgery. Morbidity defined by Postoperative Morbidity Survey (POMS), compared between patients with early elevated troponin within the first 24 h after surgery vs patients in whom troponin remained ≤14 ng L−1. †Two of 25 patients with myocardial ischaemia and 5/25 with new arrhythmia received anticoagulation. Data are presented as n (%). All comparisons made by two-tailed Fisher's exact test. CI, confidence interval; OR, odds ratio.
| Troponin ≥15 ng L−1 | Troponin <15 ng L−1 | OR (95% CI) | P-value | |
|---|---|---|---|---|
| Any POMS morbidity | 494 (49.8) | 1127 (33.7) | 1.95 (1.69–2.25) | <0.0001 |
| Pulmonary | 109 (11.0) | 275 (8.2) | 1.38 (1.09–1.74) | <0.0001 |
| Supplemental oxygen | 107 (10.8) | 271 (8.1) | 1.37 (1.08–1.74) | |
| Ventilation | 12 (1.2) | 18 (0.5) | 2.26 (1.09–4.71) | |
| Infection | 133 (13.4) | 275 (8.2) | 1.68 (1.39–2.02) | <0.001 |
| Antibiotics | 196 (19.8) | 428 (12.8) | 1.73 (1.38–2.16) | |
| Fever | 38 (3.8) | 76 (2.3) | 1.71 (1.15–2.54) | |
| Renal | 312 (31.5) | 643 (19.2) | 1.93 (1.64–2.26) | <0.001 |
| Oliguria | 16 (1.6) | 9 (0.3) | 6.07 (2.68–13.79) | |
| Catheterisation | 307 (30.9) | 639 (19.2) | 1.90 (1.62–2.23) | |
| Gastrointestinal | 116 (11.7) | 361 (10.8) | 1.09 (0.88–1.37) | 0.43 |
| Nausea/vomiting | 79 (8.0) | 280 (8.4) | 0.95 (0.73–1.23) | |
| Intolerant of enteral feed | 71 (7.2) | 172 (5.1) | 1.42 (1.07–1.89) | |
| Cardiovascular | 87 (8.8) | 84 (2.5) | 3.73 (2.74–5.08) | <0.001 |
| Myocardial infarction | 26 (2.6) | 11 (0.3) | 8.15 (4.01–16.56) | |
| Myocardial ischaemia | 12 (1.2) | 7 (0.2) | 5.84 (2.29–14.86) | |
| Hypotension | 27 (2.7) | 26 (2.3) | 3.57 (2.07–6.15) | |
| Pulmonary oedema | 2 (0.2) | 1 (0.03) | 6.75 (0.61–74.5) | |
| Arrhythmia | 33 (3.3%) | 30 (0.9) | 3.80 (2.31–6.26) | |
| Anticoagulation† | 25 (2.5%) | 33 (1.0) | 2.59 (1.54–4.38) | |
| Neurological | 30 (3.0%) | 31 (0.9) | 3.33 (2.01–5.53) | <0.001 |
| Coma | 7 (0.7%) | 4 (0.12) | 5.93 (1.73–20.31) | |
| Delirium | 22 (2.2%) | 23 (0.69) | 2.87 (1.47–5.60) | |
| Stroke | 4 (0.4%) | 8 (0.24) | 2.41 (0.77–7.62) | |
| Wound | 12 (1.2%) | 69 (2.1) | 0.58 (0.31–1.08) | 0.08 |
| Dehiscence | 4 (0.4%) | 6 (0.18) | 2.25 (0.63–8.00) | |
| Pus | 10 (1.0%) | 66 (1.97) | 0.56 (0.26–0.99) | |
| Haematological | 45 (4.5%) | 67 (2.0) | 2,32 (1.58–3.41) | <0.001 |
| Packed red cells | 44 (4.4%) | 65 (1.9) | 2.34 (1.59–3.46) | |
| Products | 5 (0.5%) | 7 (0.2) | 2.41 (0.77–7.62) | |
| Pain | 29 (2.9%) | 70 (2.1) | 1.41 (0.91–2.18) | 0.15 |
| Regional analgesia | 37 (3.7%) | 121 (3.6) | 1.18 (0.93–1.51) | |
| Parental opioids | 96 (9.7%) | 278 (8.3) | 1.39 (0.88–2.19) | |
| Mobility | ||||
| Bedbound | 146 (14.7%) | 226 (6.8) | 2.38 (1.91–2.97) | <0.001 |
| Unaided | 491 (49.5%) | 2193 (65.6) |