Table 5.
Accuracy of ProtHint for the D. melanogaster genome: sensitivity and specificity of hints to introns, start and stop codons
| Level of exclusion of reference proteins | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Species | Subgenus | Family | Order | Phylum | ||||||
| All reported | High confidence | All reported | High confidence | All reported | High confidence | All reported | High confidence | All reported | High confidence | |
| Intron Sn | 79.8 | 74.6 | 72.8 | 62.6 | 66.2 | 54.3 | 49.7 | 34.4 | 35.8 | 20.9 |
| Intron Sp | 83.5 | 98.9 | 79.6 | 98.8 | 79.5 | 98.8 | 80.5 | 99.0 | 88.4 | 99.5 |
| Start Sn | 70.3 | 60.7 | 49.8 | 36.5 | 37.7 | 29.2 | 22.3 | 15.9 | 14.1 | 9.7 |
| Start Sp | 79.5 | 97.4 | 75.6 | 96.7 | 71.6 | 95.6 | 73.4 | 94.5 | 75.0 | 93.5 |
| Stop Sn | 75.3 | 68.4 | 56.7 | 45.2 | 44.7 | 36.9 | 26.7 | 19.8 | 15.8 | 11.2 |
| Stop Sp | 94.8 | 99.3 | 94.2 | 98.8 | 92.8 | 98.5 | 94.5 | 98.9 | 95.8 | 99.2 |
The results are shown for all reported hints or just high-confidence hints. The Sn and Sp values are computed based on genome annotation of a full complement of introns, gene starts and stops, including alternative isoforms. Results for all tested species are shown in Supplementary Table S7.