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. 2020 Mar 27;182(6):583–594. doi: 10.1530/EJE-19-0762

Table 2.

Core study baseline demographics by comorbidity group. Data based on 198 patients in the core baseline population.

Glucose-related disorders Endocrine-related disorders Vascular disorders Lipid-related disorders All other acromegaly-related disorders
n 145 127 80 56 111
Mean age, years (s.d.) 47.1 (14.0) 45.8 (13.7) 51.9 (12.2) 52.3 (13.6) 48.6 (12.6)
Gender, n (%)
 Male
 Female
59 (40.7)
86 (59.3)
56 (44.1)
71 (55.9)
35 (43.8)
45 (56.3)
17 (30.4)
39 (69.6)
41 (36.9)
70 (63.1)
Mean weight, kg (s.d.) 85.4 (18.9) 86.6 (19.9) 89.9 (20.1) 85.6 (19.3) 85.8 (20.9)
Mean BMI, kg/m2 (s.d.) 29.9 (6.0) 29.8 (5.9) 31.5 (6.2) 31.1 (5.7) 29.9 (6.2)
Baseline diabetic status,* n (%)
 Diabetic
 Pre-diabetic
 Normal glucose tolerance
 Missing
104 (71.7)
41 (28.3)
0 (0.0)
0 (0.0)
94 (74.0)
20 (15.7)
13 (10.2)
0 (0.0)
64 (80.0)
14 (17.5)
1 (1.3)
1 (1.3)
46 (82.1)
7 (12.5)
3 (5.4)
0 (0.0)
81 (73.0)
21 (18.9)
9 (8.1)
0 (0.0)
Mean baseline GH, µg/L (s.d.) 12.7 (23.8) 12.4 (22.9) 10.3 (13.9) 9.0 (15.8) 10.6 (20.7)
Mean baseline IGF-I, x ULN (s.d.) 2.9 (1.1) 2.7 (1.1) 3.1 (1.1) 3.0 (1.1) 2.9 (1.1)

*See Methods section for definitions of diabetic status.