Table 2.
Glucose-related disorders | Endocrine-related disorders | Vascular disorders | Lipid-related disorders | All other acromegaly-related disorders | |
---|---|---|---|---|---|
n | 145 | 127 | 80 | 56 | 111 |
Mean age, years (s.d.) | 47.1 (14.0) | 45.8 (13.7) | 51.9 (12.2) | 52.3 (13.6) | 48.6 (12.6) |
Gender, n (%) | |||||
Male Female |
59 (40.7) 86 (59.3) |
56 (44.1) 71 (55.9) |
35 (43.8) 45 (56.3) |
17 (30.4) 39 (69.6) |
41 (36.9) 70 (63.1) |
Mean weight, kg (s.d.) | 85.4 (18.9) | 86.6 (19.9) | 89.9 (20.1) | 85.6 (19.3) | 85.8 (20.9) |
Mean BMI, kg/m2 (s.d.) | 29.9 (6.0) | 29.8 (5.9) | 31.5 (6.2) | 31.1 (5.7) | 29.9 (6.2) |
Baseline diabetic status,* n (%) | |||||
Diabetic Pre-diabetic Normal glucose tolerance Missing |
104 (71.7) 41 (28.3) 0 (0.0) 0 (0.0) |
94 (74.0) 20 (15.7) 13 (10.2) 0 (0.0) |
64 (80.0) 14 (17.5) 1 (1.3) 1 (1.3) |
46 (82.1) 7 (12.5) 3 (5.4) 0 (0.0) |
81 (73.0) 21 (18.9) 9 (8.1) 0 (0.0) |
Mean baseline GH, µg/L (s.d.) | 12.7 (23.8) | 12.4 (22.9) | 10.3 (13.9) | 9.0 (15.8) | 10.6 (20.7) |
Mean baseline IGF-I, x ULN (s.d.) | 2.9 (1.1) | 2.7 (1.1) | 3.1 (1.1) | 3.0 (1.1) | 2.9 (1.1) |
*See Methods section for definitions of diabetic status.