Table 5.
Univariate and Multivariate Cox analyses of treatment methods for OS after PSM
| Before PSM | After PSM | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | ||||||
| TNM stage | Treatment | P | HR | 95%CI | P | P | HR | 95%CI | P |
| T1-3N0M0 | < 0.001 | 0.038 | 0.048 | 0.176 | |||||
| Only surgery | Reference | Reference | Reference | Reference | Reference | Reference | |||
| Neoadjuvant radiotherapy | 1.486 | 1.315–1.679 | 0.038 | 1.164 | 0.934–1.449 | 0.176 | |||
| T1-3N0M0 | 0.016 | 0.006 | 0.039 | 0.125 | |||||
| Neoadjuvant radiotherapy | Reference | Reference | Reference | Reference | Reference | Reference | |||
| Adjuvant radiotherapy | 0.809 | 0.695–0.941 | 0.006 | 0.807 | 0.649–1.035 | 0.125 | |||
| T1-3N0M0 | 0.001 | 0.001 | 0.034 | 0.025 | |||||
| Surgery plus chemotherapy | Reference | Reference | Reference | Reference | Reference | Reference | |||
| Neoadjuvant radiotherapy | 1.285 | 1.107–1.491 | 0.001 | 1.280 | 1.045–1.574 | 0.025 | |||
| T1-3N + M0 | 0.002 | 0.008 | 0.049 | 0.036 | |||||
| Only surgery | Reference | Reference | Reference | Reference | Reference | Reference | |||
| Neoadjuvant radiotherapy | 0.795 | 0.671–0.942 | 0.008 | 0.618 | 0.429–0.863 | 0.036 | |||
| T1-3N + M0 | 0.019 | 0.015 | 0.040 | 0.022 | |||||
| Adjuvant radiotherapy | Reference | Reference | Reference | Reference | Reference | Reference | |||
| Neoadjuvant radiotherapy | 1.047 | 1.013–1.706 | 0.015 | 1.364 | 1.046–1.777 | 0.022 | |||
| T1-3N + M0 | 0.035 | 0.795 | 0.021 | 0.541 | |||||
| Surgery plus chemotherapy | Reference | Reference | Reference | Reference | Reference | Reference | |||
| Neoadjuvant radiotherapy | 1.023 | 0.863–1.212 | 0.795 | 1.083 | 0.838–1.400 | 0.541 | |||
| T4NxM0 | < 0.001 | < 0.001 | < 0.001 | < 0.001 | |||||
| Only surgery | Reference | Reference | Reference | Reference | Reference | Reference | |||
| Neoadjuvant radiotherapy | 0.459 | 0.349–0.602 | < 0.001 | 0.466 | 0.331–0.657 | < 0.001 | |||
| T4NxM0 | < 0.001 | < 0.001 | 0.002 | 0.002 | |||||
| Adjuvant radiotherapy | Reference | Reference | Reference | Reference | Reference | Reference | |||
| Neoadjuvant radiotherapy | 0.590 | 0.445–0.781 | < 0.001 | 0.589 | 0.419–0.830 | 0.002 | |||
| T4NxM0 | < 0.001 | 0.040 | 0.028 | 0.028 | |||||
| Surgery plus chemotherapy | Reference | Reference | Reference | Reference | Reference | Reference | |||
| Neoadjuvant radiotherapy | 0.752 | 0.573–0.987 | 0.040 | 0.707 | 0.519–0.963 | 0.028 | |||
PSM Propensity score matching, OS Overall Survival, CI Confidence intervals, HR Hazard ratios