Table 2.
Body weight, daily food intake and weights of retroperitoneal visceral adipose tissue, lumbar subcutaneous adipose tissue, interscapular brown adipose tissue, heart, kidneys, adrenal glands, spleen, liver, gastrocnemius, and soleus of mice fed either a standard diet (chow) or a high fat/high sucrose diet (HFHS) supplemented or not with carob fruit extract (CSAT+®) for 26 weeks. Data are represented as mean ± SEM. (n = 12 mice/group). * p < 0.05 vs. chow; ** p < 0.01 vs. chow; *** p < 0.001 vs. chow; # p < 0.05 vs. HFHS; ## p < 0.01 vs. HFHS.
| Chow | HFHS | HFHS + CSAT+® | |
|---|---|---|---|
| Body weight (g) | 29.7 ± 0.54 | 46.4 ± 1.6 *** | 48.7 ± 1.3 *** |
| Food intake (g/mouse/day) | 3.8 ± 0.03 | 2.8 ± 0.02 *** | 2.9 ± 0.03 *** |
| Visceral Retroperitoneal adipose tissue | 372 ± 35.3 | 1556 ± 67.3 *** | 1414 ± 79.2 *** |
| (mg/cm) | |||
| Subcutaneous lumbar adipose tissue (mg/cm) | 125.6 ± 8.5 | 945 ± 76.3 *** | 873 ± 93.2 *** |
| Interescapular Brown adipose tissue (mg/cm) | 67.2 ± 5.5 | 122 ± 13.7 *** | 174 ± 11.8 *** ## |
| Heart (mg/cm) | 107.6 ± 4.4 | 130 ± 4.6 ** | 113 ± 4.1 # |
| Kidneys (mg/cm) | 205.9 ± 4.9 | 257 ± 12.4 ** | 234 ± 9.1 |
| Adrenal glands (mg/cm) | 1.3 ± 0.1 | 1.80 ± 0.15 * | 1.75 ± 0.11 * |
| Spleen (mg/cm) | 39.9 ± 2.6 | 51.4 ± 4.5 ** | 48.7 ± 2.7 ** |
| Liver (mg/cm) | 620 ± 20.5 | 896 ± 62.3 * | 931 ± 74.6 ** |
| Gastrocnemious (mg/cm) | 78.5 ± 2.6 | 83.2 ± 2.5 | 80.3 ± 2.4 |
| Soleus (mg/cm) | 4.9 ± 0.2 | 7.3 ± 0.6 ** | 5.7 ± 0.3 # |