Table 1.

Enzyme and their specific bond cleavage preferences.

Enzymes	Bond Cleave	Reference
Pepsin	N-terminal of aromatic amino acids phenylalanine, tryptophan and tyrosine	[4,8]
Trypsin	Lysyl or arginyl peptide bond to expose lysine or arginine	[10]
Chymotrypsin	Aromatic or large hydrophobic amino acid residues such as tyrosine, phenylalanine, tryptophan, leucyl, methionyl, asparaginyl, and glutamyl	[4,8,60]
Elastase	Glycine and alanine of elastin	[4,8]
Carboxypeptidase A	Peptide bond adjacent to the C-terminal end of a polypeptide chain,	[4,8]
Carboxypeptidase B	Basic amino acids from the C-terminal end of polypeptide chains	[8]
Collagenase	Alpha peptides and hydrogen bonds in the superhelix of tropocollagen and collagen	[61]