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. 2020 Apr 17;9(4):329. doi: 10.3390/antiox9040329

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Prdx6^-/- mice showed altered senescence genes profile. (a) Heatmap of expression changes in 84 key genes involved in the initiation and progression of cellular senescence in gastrocnemius skeletal muscle of Prdx6^-/- mice. (b–e) Detailed expression levels of the indicated genes and pathways modulated in Prdx6^-/- compared to control group. Bar graphs report the average mRNA levels reported as mean ± SD with the respective p-values automatically calculated by the QIAGEN program. All values were normalized with internal controls. * p < 0.05 (n = 5 mice per group).