Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 17;9(4):329. doi: 10.3390/antiox9040329

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Suppression of Prdx6-reduced MyoD-mediated muscle differentiation. (a) MyoD gene expression was evaluated in gastrocnemius of wt (white bar) and Prdx6^-/- (black bar) mice. (b,c) MyoD gene and protein levels were tested in murine myoblasts cells (C2C12) stably silenced for Prdx6 (Prdx6^KD) (white bar) and in control cells (Scramble, Scr) (black bar). (d) Murine myoblasts cells differentiation at both 4× and 40× of magnification. (e) Protein phosphorylation levels of mTOR (p-mTOR) in gastrocnemius of Prdx6^-/- and wt mice were analyzed. (f) Phosphorylation levels of p38 (p-p38) were measured in muscle of Prdx6^-/- and wt mice. Results are expressed as mean ± SE. * p < 0.05, ** p < 0.005; *** p < 0.0005 using Student t test. Graphs illustrate one of three separate studies, all yielding similar results (n = 5 mice per group). a.u. = arbitrary units.