Table 2.
Age | BMI | HbA1c | TGL | TC | |
(years) | (kg/m2) | (%) | (mg/dL) | (mg/dL) | |
| |||||
rs495366, GG vs AG vs AA | −0.03; 0.709 | 0.02; 0.813 | −0.00; 0.945 | −0.05; 0.474 | 0.00; 0.957 |
rs495366, GG vs A_ | −0.01; 0.884 | 0.00; 0.960 | −0.02; 0.768 | −0.02; 0.745 | 0.02; 0.766 |
rs495366, G_ vs AA | −0.07; 0.332 | 0.06; 0.457 | 0.06; 0.436 | −0.12; 0.094 | 0.06; 0.396 |
MMP-1, pg/mL | 0.05; 0.511 | 0.05; 0.499 | 0.10; 0.181 | 0.05; 0.537 | −0.03; 0.727 |
| |||||
Creatinin, | CRP, | TSH, | Total PSA, | MMP−1, | |
mg/dL | mg/L | mU/L | ng/mL | ng/mL | |
| |||||
rs495366, GG vs AG vs AA | −0.09; 0.237 | −0.09; 0.249 | 0.03; 0.714 | −0.06; 0.431 | −0.14; 0.065 |
rs495366, GG vs A_ | −0.06; 0.433 | −0.06; 0.414 | 0.01; 0.935 | −0.04; 0.605 | −0.11; 0.134 |
rs495366, G_ vs AA | −0.14; 0.059 | −0.13; 0.085 | 0.08; 0.252 | −0.09; 0.208 | −0.15; 0.045 |
MMP-1, ng/mL | 0.11; 0.154 | 0.10; 0.168 | 0.01; 0.883 | 0.02; 0.753 | − |
Spearman's correlation test was used. Data are expressed in correlation index and significance level (two digits represent r; three digits represent P). BMI: body mass index; HbA1c: glycated hemoglobin type-A1c; MMP-1: matrix metalloproteinase-1; TGL: triglycerides; TC: total cholesterol; TSH: thyroid stimulating hormone; PSA: prostate-specific antigen. Individuals with the GG, AG, and AA genotypes were, respectively, represented by 1, 2, and 3 in the analysis with all groups, whereas G homozygotes and carriers of the A-allele were represented by 1 and 2 in this order in the subsequent analysis. Significance threshold was set at P ≤ 0.05.