Table 2.
Predictors of treatment failure among people living with HIV in ACSH, Northern Ethiopia, 2017.
| Variables | Treatment failure | AHR | 95% CI | p value | ||
|---|---|---|---|---|---|---|
| No (%) | Yes (%) | |||||
| ART regimen | Non-AZT-based | 495 (67.3) | 22 (62.9) | 1 | 1 | 1 |
| AZT-based | 240 (32.7) | 13 (371) | 16.95 | 3.02-95.1 | 0.001∗ | |
|
| ||||||
| Baseline CD4 count | ≤200 | 539 (73.3) | 26 (74.3) | 1 | 1 | 1 |
| 200-300 | 124 (16.9) | 3 (8.6) | 1.25 | 0.26-6.02 | 0.781 | |
| ≥301 | 72 (9.8) | 6 (17.1) | 0.199 | 0.05-0.76 | 0.018∗ | |
|
| ||||||
| Sex | Female | 422 (57.4) | 20 (57.1) | 1 | 1 | 1 |
| Male | 313 (42.6) | 15 (42.9) | 0.622 | 0.27-1.45 | 0.272 | |
|
| ||||||
| Baseline functional status | Ambulatory | 185 (25.2) | 18 (51.4) | 1 | 1 | 1 |
| Working | 474 (64.5) | 13 (37.1) | 1.04 | 0.29-3.47 | 0.995 | |
| Bedridden | 76 (10.3) | 4 (11.4) | 0.131 | 0.029-0.596 | 0.009∗ | |
|
| ||||||
| Baseline WHO stage | T1 and T2 | 208 (28.3) | 2 (5.7) | 1 | 1 | 1 |
| T3 | 391 (53.2) | 19 (54.3) | 0.915 | 0.155-5.4 | 0.922 | |
| T4 | 136 (18.5) | 14 (40) | 3.4 | 0.42-27.52 | 0.251 | |
Note: AHR: adjusted hazard ratio; CI: confidence interval; ART: antiretroviral therapy; WHO: World Health Organization; AZT: zidovudine. ∗Statistical significance at p < 0.05.