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Probability of target attainment at different cefepime minimum inhibitory concentrations (MICs) for the first 24 h (h) of therapy (maximum recommended dosages for adult and pediatric patients)
| Cefepime regimen | Cefepime MICs (mg/L) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Dose (mg) | Dosing interval (h) | Infusion time (h) | 0.25 (%) | 0.5 (%) | 1 (%) | 2 (%) | 4 (%) | 8 (%) | 16 (%) | 32 (%) |
| 2000 | 8 | 0.5 | 100 | 99.5 | 97.6 | 94.3 | 78.5 | 36.6 | 5.5 | 0.3 |
| 800 | 8 | 0.5 | 93.6 | 81.1 | 75.2 | 58.8 | 33.1 | 11.4 | 1.7 | 0.3 |
800 mg is based on 50 mg/kg
