Table 2.
Oxidative stress markers among neonates with RDS and control groups
| Variables | Control group (n = 40) | RDS group (n = 40) | P value | |||
|---|---|---|---|---|---|---|
| Day 0 | Day 3 | RDS Day 0 vs. control | RDS Day 3 vs. control | RDS Day 0 vs. RDS Day 3 | ||
| TAC (mmol/L) | 3.3 ± 1.1 | 2.58 ± 0.81 | 1.1 ± 0.43 | <0.001 | <0.001 | <0.001 |
| MDA (nmol/mL) | 8.8 ± 2.5 | 12.3 ± 4.3 | 20.4 ± 5.1 | 0.031 | <0.001 | <0.001 |
| AOPPs (ng/mL) | 27.0 ± 15.5 | 82.6 ± 48.0 | 196.3 ± 63.1 | <0.001 | <0.001 | <0.001 |
| 8-OHdG (pg/ml) | 1200.0 ± 823.3 | 2562.5 ± 1166.8 | 6200.0 ± 2420.0 | <0.001 | <0.001 | <0.001 |
| Copper (mg/L) | 0.71 ± 0.47 | 0.51 ± 0.19 | 0.35 ± 0.1 | 0.006 | <0.001 | 0.262 |
| Zinc (mg/dL) | 14.2 ± 6.1 | 9.1 ± 4.5 | 5.1 ± 2.2 | 0.003 | <0.001 | <0.001 |
Data were expressed as mean plus or minus SD, where ANOVA with post hoc test was used for comparison between three groups
RDS respiratory distress syndrome, TAC total antioxidant capacity, MDA malondialdehyde, AOPPs advanced oxidation protein products, 8-OHdG 8-hydroxy-desoxyguanosine, ANOVA analysis of variance