Table 1.
Patient characteristics and details of 5% CO2 inhalation.
| Infant no. | Gest. age (weeks) | Birth weight (g) | Apgar 10’ | Blood gas values on admission | Admission (h of life) | Age to target temp. 33.5 °C (h of life) | Age at intub. (h of life) | 5% CO2 inhalation | Blood gas values at the start of 5% CO2 inhalation | H of life until BD <5 mM | H of life until pH > 7.25 | Percentage of time spent in the target PCO2 range | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PCO2 (mm Hg) | pH | Start (h of life) | Duration (h) | PCO2 (mm Hg) | Lactate (mmol/L) | BD (mmol/L) | pH | ||||||||||
| 1 | 40 | 2840 | 8 | 27 | 7.31 | 4.0 | 3.3 | 2.3 | 5.6 | 7.7 | 26 | 11 | 12.7 | 7.34 | 13.0 | 8.1 | 96.5 |
| 2 | 40 | 2900 | 8 | 26 | 7.25 | 2.6 | 4.8 | 3.2 | 5.4 | 0.6 | 30 | 8 | 6.9 | 7.38 | 6.0 | 3.9 | 44.6 |
| 3 | 38 | 3850 | 8 | 35 | 7.33 | 3.2 | 3.2 | 2.5 | 4.9 | 7.6 | 30 | 5 | 6.4 | 7.40 | 12.3 | 3.2 | 95.2 |
| 4 | 40 | 3690 | 6 | 28 | 7.10 | 2.1 | 1.6 | 0.2 | 4.9 | 12.0 | 27 | 12 | 15.6 | 7.25 | 53.6 | 18.0 | 95.5 |
| 5 | 39 | 4050 | 6 | 32 | 7.35 | 2.4 | 3.4 | 1.6 | 3.9 | 1.5 | 33 | 8 | 6.9 | 7.35 | 5.1 | 1.5 | 63.2 |
| 6 | 39 | 3300 | - | 21 | 7.33 | 1.8 | 4.6 | 0.1 | 6.0 | 12.0 | 33 | 6 | 9.6 | 7.31 | 59.8 | 59.8 | 81.1 |
| 7 | 41 | 3210 | 6 | 34 | 7.26 | 3.1 | 3.8 | 1.8 | 4.7 | 4.6 | 39 | 7 | 9.9 | 7.25 | 9.2 | 15.4 | 98.7 |
| 8 | 38 | 3230 | 3 | 29 | 7.30 | 4.0 | 3.7 | 0.2 | 6.1 | 12.0 | 38 | 5 | 8.7 | 7.28 | 29.9 | 20.3 | 97.9 |
| 9 | 40 | 2490 | 4 | 42 | 7.30 | 3.7 | 2.8 | 1.5 | 6.0 | 6.0 | 33 | 13 | 16.6 | 7.17 | 11.9 | 10.1 | 92.3 |
| 10 | 37 | 3100 | 5 | 34 | 7.31 | 3.4 | 4.2 | 0.2 | 6.6 | 12.0 | 40 | 5 | 6.9 | 7.30 | 23.0 | 6.9 | 95.0 |
| Median (range) | 40 (37–41) | 3220 (2490–4050) | 6 (3–8) | 31 (21–42) | 7.31 (7.10–7.35) | 3.2 (1.8–4.0) | 3.5 (1.6–4.8) | 1.6 (0.1–3.2) | 5.5 (3.9–6.6) | 7.7 (0.6–12.0) | 33 (26–40) | 8 (5–13) | 9.2 (6.4–16.6) | 7.31 (7.17–7.40) | 12.6 (5.1–59.8) | 9.1 (1.5–59.8) | 95.1 (44.6–98.5) |