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. 2020 May 5;10(5):e035844. doi: 10.1136/bmjopen-2019-035844

Table 4.

Symptoms of SSPedi-BR and comparison among the Pediatric Quality of Life Inventory scores (n=116)

SSPedi-BR symptoms P value* Domains
Emotional School Physical Social
Mean (SD) Mean (SD) Mean (SD) Mean (SD)
Feeling disappointed or sad
 No 0.001 73.7 (20.0) 72.3 (18.6) 64.0 (29.7) 82.2 (18.6)
 Yes 55.0 (18.5) 65.3 (15.0) 61.2 (22.9) 72.7 (24.1)
 Effect size 0.98 0.41 0.22 0.4
 P value** <0.001 0.083 0.657 0.038
Feeling scared or worried
(reflective)
 No <0.001 74.7 (19.5) 71.3 (17.3) 63.3 (27.8) 77.7 (22.7)
 Yes 55.7 (19.2) 67.8 (18.4) 62.6 (27.3) 81.2 (15.2)
 Effect size 0.96 0.18 0.15 0.03
 P value** <0.001 0.385 0.903 0.441
Feeling cranky or angry
(do not feel like smiling)
 No <0.001 74.3 (18.1) 72.2 (14.9) 65.7 (27.9) 81.2 (18.6)
 Yes 53.2 (20.7) 65.3 (22.1) 57.5 (26.3) 74.6 (22.8)
 Effect size 1.12 0.35 0.38 0.41
 P value** <0.001 0.092 0.199 0.159
Problems with thinking or remembering things
 No 0.053 70.2 (20.8) 72.4 (16.5) 62.6 (28.5) 79.1 (20.2)
 Yes 61.6 (19.8) 64.2 (16.3) 66.9 (23.2) 72.4 (16.5)
 Effect size 0.65 0.49 0.08 0.22
 P value**
Changes in how your body
(visually) or face look
 No 0.115 72.2 (20.6) 72.7 (15.3) 63.4 (28.3) 79.4 (21.8)
 Yes 62.1 (21.2) 66.9 (19.8) 62.6 (26.9) 78.6 (18.5)
 Effect size 0.54 0.32 0.21 0.22
 P value**
Feeling tired
 No <0.001 79.6 (19.4) 78.9 (13.2) 79.6 (25.0) 88.0 (11.0)
 Yes 61.3 (19.9) 65.6 (18.1) 55.0 (24.9) 74.7 (22.1)
 Effect size 0.85 0.83 0.78 0.49
 P value** <0.001 0.001 <0.001 0.004
Mouth sores
 No 0.019 68.6 (21.6) 73.0 (17.4) 65.0 (26.9) 80.2 (21.3)
 Yes 62.1 (20.2) 56.6 (12.3) 54.4 (29.1) 73.7 (13.6)
 Effect size 0.39 1.09 0.52 0.39
 P value** 0.279 0.001 0.168 0.245
Headache
 No 0.072 71.0 (21.2) 72.3 (16.4) 65.2 (27.6) 80.7 (19.9)
 Yes 57.8 (19.4) 62.8 (19.4) 57.2 (27.6) 74.1 (20.7)
0.58 0.52 0.39 0.28
 P value**
Hurt or pain (other than headache)
 No 0.002 73.7 (19.8) 71.9 (18.3) 69.3 (26.0) 81.3 (18.4)
 Yes 57.7 (20.3) 67.0 (16.5) 53.5 (27.3) 75.5 (22.4)
 Effect size 0.73 0.27 0.64 0.23
 P value** 0.001 0.216 0.008 0.198
Tingly (small shocks) or numb hands or feet (no feeling in the hands or feet)
 No 0.114 70.9 (21.0) 71.0 (19.9) 66.7 (28.9) 80.7 (17.7)
 Yes 58.6 (19.9) 68.0 (11.8) 56.1 (22.1) 76.1 (24.8)
0.71 0.17 0.56 0.26
 P value**
Throwing up or feeling like you may throw up
 No 0.033 73.8 (21.7) 74.7 (16.5) 68.8 (22.3) 81.8 (20.6)
 Yes 61.8 (19.6) 65.8 (17.9) 58.0 (30.6) 76.6 (19.6)
 Effect size 0.62 0.51 0.45 0.23
 P value** 0.009 0.02 0.068 0.232
Feeling more or less hungry
(change in appetite) than you usually do
 No 0.425 72.0 (23.2) 69.5 (17.8) 63.4 (31.2) 78.8 (20.1)
 Yes 64.3 (19.6) 70.2 (17.8) 62.8 (24.9) 79.2 (20.4)
 Effect size 0.5 0.03 0.13 0.01
 P value**
Changes in taste (taste of the food)
 No 0.448 70.5 (22.3) 71.8 (13.1) 62.9 (28.1) 78.1 (19.5)
 Yes 64.7 (20.3) 68.3 (20.9) 63.2 (26.5) 79.8 (20.9)
 Effect size 0.23 0.19 0.01 0.01
 P value**
Constipation (hard to poop)
 No 0.018 69.4. (21.4) 73.7 (13.9) 66.0 (26.9) 80.8 (20.3)
 Yes 61.5 (20.4) 59.0 (22.9) 53.3 (28.0) 73.8 (19.2)
 Effect size 0.51 0.77 0.47 0.32
 P value** 0.138 0.001 0.086 0.162
Diarrhoea (watery, runny poop)
 No 0.628 66.7 (21.8) 70.3 (17.2) 63.5 (27.8) 78.7 (20.6)
 Yes 73.7 (15.7) 66.2 (23.1) 58.2 (25.7) 82.5 (19.4)
 Effect size 0.16 0.2 0.27 0.18
 P value**
Severity degree P value*
 Low <0.001
 High
 Effect size 3.02 7.73 1.49 2.99
 P value** <0.001 0.037 0.035 0.296

Self-reported version. *MANOVA (Pillai’s trace), **post-hoc test (Bonferroni).

SSPedi-BR, Rastreamento de Sintomas em Pediatria Brasileiro.