Table 2.
CSFV-neutralizing antibody responses in pmE2:pFc2 vaccinated piglets
| Age | 40-day | 60-day | 80-day | 110-day | 150-day | 170-day | |
|---|---|---|---|---|---|---|---|
| Piglet ID# | 1st injection | 2nd injection | 20 days post-boosting | 60 days post-boosting | 90 days post-boosting | 110 days post-boosting | |
| PBS control | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 2 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Ave. VNA titers (log2) | 0 | 0 | 0.0 | 0.0 | 0.0 | 0.0 | |
| pmE2:pFc2 | 35 | 0 | 3 | 10 | 8 | 6 | 6 |
| 36 | 0 | 8 | 11 | 7 | 7 | 6 | |
| 38 | 0 | 6 | 10 | 7 | 6 | 5 | |
| 39 | 0 | 5 | 12 < | 8 | 8 | 7 | |
| Ave. VNA titers (log2) | 0 | 5.5 | 10.75 | 7.5 | 6.75 | 6 |
VNA virus neutralizing antibody, CSFV neutralizing antibody titers were measured as described in the Materials and methods section