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. 2020 Jan 13;21(2):135–144. doi: 10.1038/s41590-019-0571-2

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© The Author(s), under exclusive licence to Springer Nature America, Inc. 2020

This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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Extended Data Fig. 3 — a, Representative confocal images (scale, 2 μm) and b, quantification of granule content (top) and MPO intensity (bottom) in CXCR2-deficient neutrophils upon LPS or PMA stimulation. Granule loss indicates that CXCR2-deficient neutrophils are responsive to inflammatory stimuli; n = 15 cells per group. Data are shown as mean ± SEM. **; p < 0.01; ***, p < 0.001, as determined.