Table 4.
Checkpoint conditions X1/X2 | Y1 (nm) | Y2 (%) | ||||
---|---|---|---|---|---|---|
Obser | Pred | Error (%) | Obser | Pred | Error (%) | |
2.50/1.73* | 256.3 | 261.9 | − 2.18 | 73.1 | 73.9 | − 1.09 |
2.75/1.44 | 290.0 | 276.8 | 4.55 | 73.4 | 74.1 | − 0.95 |
0.50/0.38 | 338.9 | 361.0 | − 6.52 | 59.6 | 62.2 | − 4.35 |
5.0/2.5 | 550.6 | 584.0 | − 6.07 | 72.3 | 71.5 | 1.11 |
Optimized batch was prepared in sextet (n = 6), and the mean values with SD for Y1 and Y2 are 256.3 ± 10.5 nm and 73.1 ± 1.5%, respectively
Obser, experimentally observed values; Pred, values predicted by the mathematical model
*Represents optimized formulation