Table 1.
Characteristics | n=36 |
Gender, male:female (%) | 26:10 (72:28) |
IBD phenotype | |
Ulcerative colitis/IBD-U | 18 (50%) |
Left-sided | 11 |
Extensive | 7 |
Crohn’s disease | 18 (50%) |
Ileal | 6 |
Colonic | 4 |
Ileocolonic | 8 |
Median age, years (range) | 44 (17–70) |
Concomitant immunomodulator use at baseline | 18 (50%) |
Thiopurine | 17 |
Methotrexate | 1 |
Prior anti-TNF exposure | |
Naïve | 5 (14%) |
Exposed | 31 (86%) |
Corticosteroid use at baseline | 6 (16%) |
Median duration of vedolizumab treatment before dose intensification, months (range) | 7 (3–21) |
Median duration of vedolizumab treatment after dose intensification, months (range) | 7 (2–25) |
IBD, inflammatory bowel disease; IBD-U, IBD-unclassified; TNF, tumour necrosis factor.