Table 4.

Difference in plaque score per 1 SD increase in each adiposity measure: pooled results from the two studies

	Model 1 slope (95% CI)	P value	Model 2 slope (95% CI)	P value	Model 3 slope (95% CI)	P value
Men (n=2200)
st BMI	−0.021 (−0.069 to 0.026)	0.38	−0.008 (−0.055 to 0.039)	0.74	−0.091 (−0.143 to −0.040)	<0.001
st WHR	0.033 (−0.025 to 0.090)	0.26	0.013 (−0.043 to 0.069)	0.65	−0.076 (−0.136 to −0.015)	0.01
Women (n=2862)
st BMI	0.023 (−0.009 to 0.056)	0.16	0.023 (−0.010 to 0.055)	0.17	−0.056 (−0.091 to −0.021)	0.002
st WHR	0.131 (0.093 to 0.169)	<0.001	0.109 (0.070 to 0.147)	<0.001	0.025 (−0.018 to 0.067)	0.25

Model 1: adjusted for categorical age (5 years) and study, model 2: adjust for variables in model 1 plus potential confounders (smoking and education), model 3: adjusted for variables in model 2 plus potential mediators (systolic blood pressure, HDL cholesterol, LDL cholesterol, glycated haemoglobin, medical history of diabetes.

HDL, high-density lipoprotein; LDL, low-density lipoprotein; St BMI, body mass index z-score; st WHR, waist-to-hip ratio z-score.