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Antiviral activity of Smp76 and its derivatives
| Source | Smp76/derivatives | IC50 (ng/ml) | |
|---|---|---|---|
| Anti-HCV | Anti-DENV | ||
| Synthetic | N-terminal 32 aa | > 10,000 | > 10,000 |
| C-terminal 44 aa (without disulfide bonds) | > 10,000 | > 10,000 | |
| Full-length 76 aa (without disulfide bonds) | > 10,000 | > 10,000 | |
| Recombinant | C-terminal 44 aa | > 10,000 | > 10,000 |
| Native or purified Smp76 | Full-length 76 aa | 10 | 10 |
