Table 4.

In vitro antifungal activity of indeno[1,2-c]pyrazol-4-ones (4a–o) against A. niger in terms of % inhibition and IC₅₀ values

Compounds	% Inhibition				IC50 (μg/mL)
	125 (μg/mL)	250 (μg/mL)	500 (μg/mL)	1000 (μg/mL)
4a	55.23	59.94	66.75	70.68	60.25
4b	49.47	58.37	65.96	71.20	154.54
4c	49.21	54.71	60.73	67.01	130.31
4d	64.13	69.89	74.34	78.27	17.58
4e	54.71	63.61	65.96	76.70	79.43
4f	69.63	74.34	80.89	84.55	14.28
4g	59.68	71.98	78.79	83.76	45.70
4h	69.63	74.34	80.89	84.55	14.29
4i	64.13	73.56	78.79	81.93	25.70
4j	54.97	63.35	72.77	75.65	74.13
4k	63.08	65.96	73.29	80.62	55.59
4l	51.30	57.32	59.42	67.01	100.00
4m	57.32	66.23	72.25	76.96	48.97
4n	63.87	70.68	74.86	78.27	18.62
4o	72.25	76.96	79.31	82.98	05.68
Fluconazole	74.08	85.60	89.73	92.40	12.73