Fig. 2.

Variations of functional mitral regurgitation severity during spontaneous breathing trials (SBT) and effect of echocardiography-guided therapy. Central functional mitral regurgitation at baseline (upper left, arrow) significantly increased during the failed spontaneous breathing trial (lower left panel, arrow). After a treatment associating diuretics and angiotensin converting enzyme inhibitors, the central mitral regurgitation which remained trivial at baseline (upper right panel, arrow) failed to significantly worsen during the second weaning trial (lower right panel, arrow), and the patient was successfully extubated