Table 3.
Hemodynamic parameters and echocardiography findings in the subset of patients who failed the first SBT but succeeded the second weaning trial
| 1st failed SBT (n = 10) |
2nd passed SBT (n = 10) |
P value | |
|---|---|---|---|
| Before weaning trials | |||
| Hemodynamic parameters | |||
| HR, bpm | 107 (92–126)* | 102 (91–114) | 0.308 |
| sBP, mmHg | 131 (108–142) | 144 (120–160) | 0.475 |
| dBP, mmHg | 82 (68–90) | 82 (77–91) | 0.477 |
| mBP, mmHg | 92 (82–111) | 102 (90–116) | 0.312 |
| Echocardiography parameters | |||
| E, cm/s | 102 (85–149) | 84 (67–127) | 0.017 |
| A, cm/s | 58 (41–110) | 62 (48–93) | 0.88 |
| E/A | 1.7 (1.2–2.7) | 1.3 (0.8–2.1) | 0.139 |
| DTE, ms | 103 (92–134) | 133 (103–184) | 0.139 |
| E′ lateral, cm/s | 11.1 (7.6–16.4) | 13.5 (8.8–15.4) | 0.646 |
| E/E′ | 8.9 (5.9–13.1) | 7.3 (5–10.4) | 0.028 |
| MR/LA area | 0.15 (0.14–0.2) | 0.11 (0.06–0.17) | 0.249 |
| LVEF, % | 30 (20–36) | 34 (27–38) | 0.161 |
| LVOT VTI, cm | 14.6 (9.3–22.6) | 15.0 (10.9–19) | 0.678 |
| TR peak velocity, m/s | 3.43 (2.69–4.52) | 3.2 (2.64–3.48) | 0.285 |
| During weaning trials | |||
| Hemodynamic parameters | |||
| HR, bpm | 131 (112–138) | 108 (99–111) | 0.011 |
| sBP, mmHg | 143 (125–168) | 133 (113–156) | 0.919 |
| dBP, mmHg | 88 (63–99) | 77 (70–78) | 0.308 |
| mBP, mmHg | 112 (72–115) | 94 (85–106) | 0.507 |
| Echocardiography parameters | |||
| E, cm/s | 122 (93–168) | 100 (85–122) | 0.009 |
| A, cm/s | 60 (34–103) | 67 (48–93) | 0.48 |
| E/A | 2.5 (1.1–3.6) | 1.5 (0.9–2.3) | 0.009 |
| DTE, ms | 81 (71–128) | 130 (97–133) | 0.093 |
| E′ lateral, cm/s | 12.5 (8.9–16.4) | 14.2 (8.5–15.6) | 0.878 |
| E/E′ | 9.3 (7.5–12.6) | 7.7 (6.2–9.9) | 0.047 |
| MR/LA area | 0.26 (0.2–0.39) | 0.11 (0.06–0.29) | 0.028 |
| LVEF, % | 26 (16–35) | 29 (26–36) | 0.401 |
| LVOT VTI, cm | 14 (8.9–20.1) | 15.5 (12.6–20) | 0.263 |
| TR peak velocity, m/s | 3.67 (3–4.18) | 2.90 (2.69–3.37) | 0.068 |
| Hydric balance | |||
| Weight difference (admission), kg | + 1.6 (− 2.1/ + 6.5) | − 5.0 (− 9.5/− 1.7) | 0.005 |
| Fluid balance (admission), ml | + 146 (− 2654/ + 4434) | − 2224 (− 7056/ + 100) | 0.005 |
HR heart rate, sBP systolic blood pressure, dBP diastolic blood pressure, mBP mean blood pressure, DTE deceleration time of mitral E wave, MR mitral regurgitation, LA left atrium, LVEF left ventricular ejection fraction, LVOT left ventricular outflow tract, VTI velocity–time integral, TR tricuspid regurgitation
*Significant difference between parameters measured under positive pressure ventilation and during the weaning trial