Table 3.
Unadjusted and adjusted odds ratios (and 95% confidence intervals) from logistic regression analyses predicting 30-day readmission
| Unadjusted OR | 95% CI | Adjusted OR | 95% CI | |
|---|---|---|---|---|
| Sex: Male vs. female | 1.087 | (0.540, 2.185) | ||
| Age (by 5-year units) | 1.003 | (0.895, 1.124) | ||
| BMI | 0.979 | (0.952, 1.007) | ||
| Active smoker: (yes vs. no) | 0.347 | (0.143, 0.841) | ||
| Length of admission (days) | 1.001 | (0.977, 1.026) | ||
| Intensive care unit admission | ||||
| (Yes vs. no) | 0.576 | (0.286, 1.160) | ||
| Intubation: (yes vs. no)a | 0.387 | (0.151, 0.988) | ||
| Primary admission reason | ||||
| Respiratory failure (yes vs. no) | 0.571 | (0.281, 1.161) | ||
| Pneumonia (yes vs. no) | 0.658 | (0.181, 2.395) | ||
| COPD exacerbation (yes vs. no) | 0.727 | (0.307, 1.722) | ||
| Overdose (yes vs. no) | < 0.001 | (< 0.001, > 999) | ||
| Sepsis (yes vs. no) | 0.474 | (0.133, 1.682) | ||
| Trauma (yes vs. no) | 1.726 | (0.153, 19.528) | ||
| Cardiac disease (yes vs. no) | 1.849 | (0.888, 3.848) | ||
| Myocardial infarction (yes vs. no) | 1.240 | (0.455, 3.384) | ||
| Congestive heart failure (yes vs. no) | 1.121 | (0.529, 2.378) | ||
| Peripheral vascular disease (yes vs. no) | 4.598 | (1.451, 14.573) | 4.779 | (1.451, 15.744) |
| Cerebrovascular disease (yes vs. no) | 0.846 | (0.173, 4.150) | ||
| Chronic pulmonary disease (yes vs. no) | 0.646 | (0.318, 1.313) | ||
| Diabetes with chronic complications (yes vs. no) | 0.806 | (0.362, 1.798) | ||
| Renal disease (yes vs. no) | 1.015 | (0.421, 2.444) | ||
| Obstructive sleep apnea (yes vs. no) | 0.813 | (0.354, 1.865) | ||
| Pulmonary disease | ||||
| COPD (yes vs. no) | 0.504 | (0.244, 1.041) | ||
| Obesity hypoventilation (yes vs. no) | 0.293 | (0.037, 2.341) | ||
| Asthma (yes vs. no) | 0.782 | (0.248, 2.469) | ||
| Interstitial lung disease (yes vs. no) | 10.974 | (1.110, 108.519) | ||
| Bronchiectasis (including CF) (yes vs. no) | > 999 | (< 0.001, > 999) | ||
| Home respiratory support | ||||
| CPAP (yes vs. no) | 1.005 | (0.347, 2.912) | ||
| BIPAP (yes vs. no) | 0.771 | (0.209, 2.849) | ||
| Oxygen | 0.801 | (0.386, 1.662) | ||
| None | ||||
| Charlson comorbidity indexb | 0.863 | (0.683, 1.090) | ||
| Discharge respiratory support | ||||
| CPAP (yes vs. no) | 1.784 | (0.509, 6.253) | ||
| BIPAP (yes vs. no) | 0.503 | (0.141, 1.792) | ||
| Oxygen (yes vs. no) | 0.932 | (0.457, 1.900) | ||
| None (yes vs. no) | 1.212 | (0.604, 2.432) | ||
| Admission or death due to hypercapnic respiratory failure | ||||
| Yes vs. no | 0.750 | (0.321, 1.755) | ||
| Maybe vs. no | 0.771 | (0.241, 2.465) | ||
| Readmission | ||||
| Yes vs. no | > 999 | (< 0.001, > 999) | ||
| Days until first readmissionc | 0.603 | (0.368, 0.989) | ||
| Number of readmissionsc | 1.111 | (0.904, 1.366) | ||
| Readmission due to hypercapnic respiratory failure | ||||
| Yes vs. no | 1.454 | (0.592, 3.572) | ||
| Maybe vs. no | 1.680 | (0.369, 7.644) | ||
| N/A vs. no | < 0.001 | (< 0.001, > 999) | ||
| Arterial blood gas valuesd | ||||
| 0.989 | (0.966, 1.013) | |||
| Bicarbonate | ||||
| ≤ 19 vs. 20–29 | 1.711 | (0.390, 7.493) | ||
| 30–39 vs. 20–29 | 1.207 | (0.575, 2.535) | ||
| 40–49 vs. 20–29 | < 0.001 | (0.001, > 999) | ||
| Hemodynamics in first 24 h | ||||
| Most extreme heart rate in first 24 h | ||||
| ≤ 69 vs. 70–119 | 2.623 | (0.981, 7.014) | 2.464 | (0.891, 6.814) |
| ≥ 120 vs. 70–119 | 2.658 | (1.109, 6.370) | 2.970 | (1.215, 7.261) |
| Lowest blood pressure | ||||
| Other vs. MAP ≥ 70 | 0.895 | (0.388, 2.066) | ||
Bold values indicate statistical significance
OR odds ratio, CI confidence interval
aAmong those admitted to the ICU (n = 103)
bBased on Quan et al. [15]
cAmong those readmitted (n = 95)
d38–41% Data missing