Table 2.
Ventilation parameters and Reynolds number for different study cases
| Mode | Ppeak (kPa) | RR (min−1) | I:E |
PEEP (kPa) |
Strategy (ml kg-1) | MVv (l) | PIF (l s−1) | PEF (l s−1) | insp (m s−1) | exp (m s−1) |
Re (insp) (–) |
Re(exp) (–) |
| PCV | 0.8 | 36 | 01:01 | 0.3 | PH (6) | 0.18 | 0.012 | 0.036 | 0.123 | 0.123 | 89 | 89 |
| PCV | 0.8 | 36 | 01:02 | 0.6 | PH (6) | 0.18 | 0.014 | 0.033 | 0.143 | 0.143 | 104 | 104 |
| PCV | 0.8 | 36 | 01:01 | 0.3 | PH (6) | 0.18 | 0.012 | 0.039 | 0.123 | 0.123 | 89 | 89 |
| PCV | 1 | 36 | 01:02 | 0.6 | PH (6) | 0.19 | 0.018 | 0.044 | 0.193 | 0.193 | 141 | 141 |
| PCV | 1.1 | 48 | 01:01 | 0.3 | PH (6) | 0.24 | 0.023 | 0.045 | 0.242 | 0.242 | 176 | 176 |
| PCV | 1.2 | 48 | 01:02 | 0.6 | PH (6) | 0.28 | 0.025 | 0.041 | 0.261 | 0.261 | 190 | 190 |
| PCV | 1 | 48 | 01:01 | 0.3 | PH (6) | 0.23 | 0.017 | 0.042 | 0.174 | 0.174 | 127 | 127 |
| PCV | 0.9 | 48 | 01:02 | 0.6 | PH (6) | 0.23 | 0.013 | 0.038 | 0.140 | 0.140 | 102 | 102 |
| PCV | 1 | 36 | 01:01 | 0.3 | SV (8) | 0.26 | 0.018 | 0.051 | 0.193 | 0.193 | 141 | 141 |
| PCV | 1 | 36 | 01:01 | 0.6 | SV (8) | 0.27 | 0.018 | 0.047 | 0.193 | 0.193 | 141 | 141 |
| PCV | 1.1 | 36 | 01:02 | 0.3 | SV (8) | 0.26 | 0.027 | 0.052 | 0.283 | 0.283 | 206 | 206 |
| PCV | 1.1 | 36 | 01:02 | 0.6 | SV (8) | 0.27 | 0.025 | 0.051 | 0.266 | 0.266 | 194 | 194 |
| PCV | 1.1 | 48 | 01:01 | 0.3 | SV (8) | 0.31 | 0.013 | 0.042 | 0.141 | 0.141 | 103 | 103 |
| PCV | 1.1 | 48 | 01:01 | 0.6 | SV (8) | 0.31 | 0.013 | 0.042 | 0.140 | 0.140 | 102 | 102 |
| PCV | 1.3 | 48 | 01:02 | 0.3 | SV (8) | 0.32 | 0.020 | 0.045 | 0.214 | 0.214 | 156 | 156 |
| PCV | 1.3 | 48 | 01:02 | 0.6 | SV (8) | 0.31 | 0.019 | 0.040 | 0.202 | 0.202 | 147 | 147 |
| Mode | Fmax (min−1) | RR (min−1) | PEEP (kPa) | Strategy (ml kg−1) | MVv (l) | PIF (l s−1) | PEF (l s−1) | insp (m s−1) | exp (m s−1) | Re(insp) (–) | Re(exp) (–) | |
| VCVCF | 2.3 | 36 | 0.3 | PH (6) | 0.18 | 0.024 | 0.026 | 0.255 | 0.277 | 185 | 201 | |
| VCVCF | 2.3 | 36 | 0.6 | PH (6) | 0.18 | 0.025 | 0.032 | 0.260 | 0.332 | 190 | 242 | |
| VCVCF | 2.1 | 48 | 0.6 | PH (6) | 0.18 | 0.023 | 0.032 | 0.247 | 0.336 | 180 | 244 | |
| VCVCF | 2.1 | 48 | 0.3 | PH (6) | 0.23 | 0.022 | 0.032 | 0.235 | 0.333 | 171 | 243 | |
| VCVCF | 2.7 | 48 | 0.3 | SV (8) | 0.33 | 0.029 | 0.043 | 0.309 | 0.452 | 225 | 329 | |
| VCVCF | 2.7 | 48 | 0.6 | SV (8) | 0.33 | 0.027 | 0.039 | 0.281 | 0.414 | 204 | 301 | |
| VCVCF | 2.8 | 36 | 0.6 | SV (8) | 0.25 | 0.028 | 0.044 | 0.291 | 0.464 | 212 | 338 | |
| VCVCF | 2.8 | 36 | 0.3 | SV (8) | 0.25 | 0.030 | 0.042 | 0.313 | 0.442 | 228 | 321 | |
| Mode | Fmax (l min−1) | RR (min−1) | PEEP (kPa) | Strategy (ml kg−1) | MVv (l) | PIF (l s−1) | PEF (l s−1) | insp (m s−1) | exp (m s−1) | Re(insp) (–) | Re(exp) (–) | |
| VCVDF | 3.2 | 36 | 0.3 | PH (6) | 0.18 | 0.022 | 0.026 | 0.231 | 0.274 | 168 | 200 | |
| VCVDF | 3.2 | 36 | 0.6 | PH (6) | 0.19 | 0.023 | 0.028 | 0.241 | 0.294 | 175 | 214 | |
| VCVDF | 2.5 | 48 | 0.3 | PH (6) | 0.22 | 0.018 | 0.027 | 0.193 | 0.280 | 141 | 204 | |
| VCVDF | 2.7 | 48 | 0.6 | PH (6) | 0.23 | 0.020 | 0.026 | 0.210 | 0.275 | 153 | 200 | |
| VCVDF | 3.2 | 36 | 0.3 | SV (8) | 0.23 | 0.025 | 0.038 | 0.263 | 0.402 | 191 | 293 | |
| VCVDF | 3.2 | 36 | 0.6 | SV (8) | 0.24 | 0.024 | 0.038 | 0.252 | 0.404 | 183 | 294 | |
| VCVDF | 2.9 | 48 | 0.6 | SV (8) | 0.32 | 0.022 | 0.038 | 0.228 | 0.403 | 166 | 293 | |
| VCVDF | 3 | 48 | 0.3 | SV (8) | 0.32 | 0.023 | 0.037 | 0.246 | 0.386 | 179 | 281 | |
PCV, pressure-controlled mode of ventilation; VCVCF, VCVDF, volume-controlled mode of ventilation with constant and descending flow, respectively; PPeak, pressure limit; RR, respiratory rate; I:E, inspiration:expiration ratio; PEEP, positive end-expiratory pressure; STRATEGY, tidal volume per kilogram of body mass; PH, permissive hypercapnia (6 ml kg−1); SV, standard ventilation (8 ml kg−1); MVV, minute ventilation set on the ventilator; Fmax, flow limit set on the ventilator; Re(insp), Re(exp), Reynold’s number for inspiration and expiration, respectively; PIF, PEF, peak inspiratory flow and peak expiratory flow; , , mean linear velocity during inspiration and expiration, respectively