Table 7.
Multivariable analysis including life-sustaining treatment limitation
| Variables | Categories | HR (95%CI) | p-value |
|---|---|---|---|
| Age | One-point increase | 1 (0.99–1.02) | 0.79 |
| Habitat (ref = not home) | Own home | 0.96 (0.85–1.08) | 0.47 |
| Gender (ref = male) | Female | 0.94 (0.84–1.04) | 0.24 |
| Reason for admission (ref = circulatory failure) | Combined respiratory/circulatory failure | 1.13 (0.94–1.36) | 0.19 |
| Emergency surgery | 0.68 (0.56–0.84) | 0.0003 | |
| Multitrauma w/wo head injury | 1.21 (0.85–1.73) | 0.28 | |
| Multitrauma without head injury | 0.91 (0.61–1.36) | 0.64 | |
| Other | 0.88 (0.73–1.06) | 0.18 | |
| Respiratory failure | 0.82 (0.69–0.97) | 0.021 | |
| Sepsis (according to Sepsis3) | 0.67 (0.55–0.81) | 0.0003 | |
| SOFA | One-point increase | 1.16 (1.14–1.17) | < 0.0001 |
| CPS | One-point increase | 0.99 (0.98–1) | 0.05 |
| CFS | One-point increase | 1.08 (1.05–1.12) | < 0.0001 |
| Withholding or withdrawal | Yes vs no | 4.25 (3.8–4.74) | < 0.0001 |