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. 2019 Oct 1;40(1):89–96. doi: 10.1038/s41372-019-0501-z

Table 2.

Results of laboratory, radiographic, ophthalmologic, and audiologic evaluation in 34 infants with congenital CMV infection and a normal physical examination at birth

Dallas Buenos Aires Total
No. of infants 14 (41%) 20 (59%) 34
No. of infants with at least 1 abnormality 7 (50%) 12 (60%) 19 (56%)
Laboratory evaluation 10 (71%) 15 (75%) 25 (71%)
 Any abnormality 4 (40%) 11 (73%) 15 (60%)
 Complete blood cell count 10 (40%) 15 (60%) 25 (100%)

 Anemia

(hematocrit; mean, range)

0

3 (20%)

(35%, 30–39%)

3 (12%)

(35%, 30–39%)

 Thrombocytopenia

(#/ml; mean, range)

2 (20%)

(33,500; 10,000–57,000)

2 (13%)

(126,000; 114,000–132,000)

4 (16%)

(78,250; 10,000–132,000)

Hepatic assessment 8 (57%) 15 (75%) 23 (92%)

 Elevated alanine aminotransferase

(U/mL; mean, range)

2 (22%)

(44.5, 43–46)

7 (78%)

(55.5, 41–74)

9 (39%)

(53, 41–74)

 Direct hyperbilirubinemia 0 0 0
Neuroimaging 14 (100%) 10 (50%) 24 (71%)
 Any abnormality 6 (43%) 5 (57%) 11 (46%)
 Cranial ultrasonography 13 (93%) 9 (90%) 22 (92%)
 Any abnormality 6 (46%) 4 (44%) 10 (45%)
 Diffuse calcifications 1 (8%) 0 1 (55%)
 Lenticulostriate vasculopathy 2 (14%) 3 (30%) 5 (23%)
 Ventriculomegaly 1 (8%) 0 1 (5%)
 Any Grade of IVH 5 (39%) 1 (11%) 6 (27%)
  Grade I IVH 5 (100%) 0 5 (83%)
  Grade II–III IVHa 0 1 (100%) 1 (17%)
 Cranial computerized tomography 1 (7%) 1 (10%) 2/24 (8%)
 Thalamic calcifications 0 1 (100%) 1 (50%)
 Brain magnetic resonance imaging 2 (14%) 5 (50%) 7/24 (29%)
 Periventricular calcifications and temporal lobe hyperlucency 0 1 (20%) 1 (14%)
 Calcifications of thalami 0 1 (20%) 1 (14%)
 Germinal matrix hemorrhage 1 (50%) 0 1 (14%)
Ophthalmological evaluation 13 (93%) 20 (100%) 33 (97%)
 Chorioretinitis 0 1 (5%) 1 (3%)
Audiologic evaluation (brainstem evoked responses) 14 (100%) 20 (100%) 34 (100%)
 Sensorineural hearing loss 6 (43%) 1 (5%) 7 (21%)
 Unilateral 3 (50%) 1 (100%) 4 (57%)
 Bilateral 3 (50%) 0 3 (43%)
 Mild 1 (17%) 0 1 (14%)
 Moderate 2 (33%) 0 2 (29%)
 Severe-profound 3 (50%) 1 (100%) 4 (57%)

aNeonate born at 27 weeks’ gestation