Table 6.
Change in serum creatinine for patients who experienced a renal failure AE (n = 8)
Patient | Serum creatinine (mg/dL) | Days elapsed | ||
---|---|---|---|---|
Baseline | Last recorded value | Increase from baseline | ||
1 | 1.1 | 11.1 | 10 | 33 |
2 | 1.8 | 2.5 | 0.7 | 49 |
3 | 0.3 | 1.4 | 1.1 | 15 |
4 | 2.6 | 2.9 | 0.3 | 15 |
5 | 1.8 | 2.3 | 0.5 | 12 |
6 | 1.2 | 3.3 | 2.1 | 11 |
7 | 1.0 | 1.4 | 0.4 | 45 |
8 | 1.7 | 5.8 | 4.1 | 13 |
Of 12 patients with bacteremia or endocarditis who experienced renal failure during telavancin therapy, two did not have CrCl measurements recorded as they were on dialysis at baseline and two were missing a baseline serum creatinine concentration
AE adverse event, CrCL creatinine clearance